If GABA is released at synapse area then what will happens :

Options

A. Depolarization of neuron
B. Repolarization of neuron
C. Hyperpolarization of neuron
D. No effect

Answer

### Step-by-Step Solution:

1. **Understanding GABA**: GABA (Gamma-Aminobutyric Acid) is a neurotransmitter that plays a crucial role in inhibitory synapses in the nervous system.

2. **Release of GABA**: When GABA is released into the synaptic cleft, it binds to specific receptors on the postsynaptic neuron.

3. **Effect on Ion Channels**: The binding of GABA to its receptors causes an increase in the influx of chloride ions (Cl⁻) into the postsynaptic neuron.

4. **Decrease in Potassium Efflux**: Additionally, the binding of GABA decreases the efflux (outflow) of potassium ions (K⁺) from the postsynaptic cell.

5. **Change in Membrane Potential**: The increase in chloride ions entering the cell and the decrease in potassium ions leaving the cell leads to a decrease in the membrane potential of the postsynaptic neuron.

6. **Hyperpolarization**: As the membrane potential becomes more negative (due to the influx of Cl⁻ and reduced efflux of K⁺), the postsynaptic neuron becomes hyperpolarized. This means it is less likely to fire an action potential.

7. **Conclusion**: Therefore, when GABA is released at the synapse, the postsynaptic neuron is hyperpolarized.

### Final Answer:
The neuron is hyperpolarized.