Brain of human differs from that of frog in having:

Options

A. Large olfactory lobe
B. Small hypothalamus
C. Small cerebellum
D. Corpus callosum

Answer

To solve the question regarding how the human brain differs from that of a frog, we will analyze the options provided and determine which one correctly identifies a structural difference.

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks how the human brain differs from the frog's brain. We need to identify a specific structure or feature that is present in humans but not in frogs.

2. **Evaluating the Options**:
- **Option 1: Large olfactory lobe**:
- The olfactory lobes are responsible for the sense of smell. While humans have larger olfactory lobes compared to frogs, this option does not highlight a unique difference.
- **Option 2: Small hypothalamus**:
- The hypothalamus is involved in various functions, including temperature regulation and hormonal control. This is not a distinguishing feature since both species have hypothalami, though their sizes may vary.
- **Option 3: Small cerebellum**:
- The cerebellum is crucial for motor control and coordination. Frogs have a well-developed cerebellum for their locomotion needs, making this option incorrect.
- **Option 4: Corpus callosum**:
- The corpus callosum is a significant structure in the human brain that connects the left and right hemispheres, facilitating communication between them. Frogs do not possess a corpus callosum, making this the correct answer.

3. **Conclusion**: The human brain differs from that of a frog in having a **corpus callosum**. This structure is essential for inter-hemispheric communication in humans, which is not present in the frog's brain.

### Final Answer:
The brain of a human differs from that of a frog in having a **corpus callosum**.