Parkinson disease is a neurodegenerative disease, caused by deterioration of neurons. It is due to deficiency of which neurotransmitter?

Options

A. Acetyl choline
B. Dopamine
C. GABA
D. Nor-epinephrine

Answer

To solve the question regarding the neurotransmitter deficiency that causes Parkinson's disease, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Parkinson's Disease**:
- Parkinson's disease is a neurodegenerative disorder characterized by the deterioration of neurons, particularly in specific areas of the brain that control movement.

2. **Identify the Role of Neurotransmitters**:
- Neurotransmitters are chemical messengers that transmit signals across synapses from one neuron to another. Different neurotransmitters play various roles in the nervous system.

3. **Evaluate the Options**:
- The question provides four options for the neurotransmitter deficiency:
- **Option 1: Acetylcholine**: This neurotransmitter is primarily involved in the parasympathetic nervous system and muscle contraction.
- **Option 2: Dopamine**: This neurotransmitter is crucial for movement control and is significantly affected in Parkinson's disease.
- **Option 3: GABA (Gamma-Aminobutyric Acid)**: This is the main inhibitory neurotransmitter in the brain, but it is not directly related to Parkinson's disease.
- **Option 4: Norepinephrine**: This neurotransmitter is involved in the body's response to stress and does not play a direct role in Parkinson's disease.

4. **Determine the Correct Answer**:
- Among the options, Dopamine (Option 2) is the neurotransmitter whose deficiency is directly linked to the symptoms and progression of Parkinson's disease. The loss of dopamine-producing neurons leads to the characteristic motor symptoms of the disease.

5. **Conclusion**:
- Therefore, the correct answer to the question is **Dopamine**.

### Final Answer:
- The deficiency of **Dopamine** is responsible for Parkinson's disease.

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