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How is a mature, functional insulin horm...

How is a mature, functional insulin hormone different from its pro-hormone form?

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Mature functional insulin is obtained b y the processing of pro-hormone which contains an extra peptide called C-peptide or connecting peptids.
It connects the A and B chains in proinsulin. This C-peptide is removed during the maturation of pro-insulin to insulin and A and B chains gets linked by disulphide linkage.
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