Select the incorrect statements regarding AIDS from the following:
I. AIDS is caused by a retrovirus have two molecules of single-stranded RNA as its genome.
II. AIDS can be successfully treated using anti-retroviral drugs
III. Macrophages act as a viral factory as it leads to the continuous production of new viral particles.
IV. In AIDS, a decrease in B-lymphocyte count is seen.

Options

A. Il and IV
B. I and III
C. I and II
D. III and IV

Answer

To solve the question regarding the incorrect statements about AIDS, we will analyze each statement one by one:

### Step-by-Step Solution:

1. **Statement I: AIDS is caused by a retrovirus that has two molecules of single-stranded RNA as its genome.**
- **Analysis:** AIDS is caused by the Human Immunodeficiency Virus (HIV), which is indeed a retrovirus. However, it has two single strands of RNA, not two molecules. This statement is **correct**.

2. **Statement II: AIDS can be successfully treated using anti-retroviral drugs.**
- **Analysis:** While anti-retroviral drugs can help manage HIV infection and prolong the life of an individual, they do not cure AIDS. Therefore, this statement is **incorrect**.

3. **Statement III: Macrophages act as a viral factory as it leads to the continuous production of new viral particles.**
- **Analysis:** HIV infects macrophages and uses them to replicate, effectively turning them into factories for producing new viral particles. This statement is **correct**.

4. **Statement IV: In AIDS, a decrease in B-lymphocyte count is seen.**
- **Analysis:** HIV primarily targets T-helper cells, which play a crucial role in the immune response, including the activation of B-lymphocytes. While T-helper cells decrease, B-lymphocyte counts may not necessarily decrease directly due to HIV. This statement is **incorrect**.

### Conclusion:
The incorrect statements regarding AIDS are:
- **Statement II**: AIDS can be successfully treated using anti-retroviral drugs.
- **Statement IV**: In AIDS, a decrease in B-lymphocyte count is seen.

### Final Answer:
The incorrect statements are **II and IV**.

---