Which of the following is an appropriate set of reactants for the preparation of 1 methoxy - 4 nitrobenzene ?

Options

A.
B.
C. Both A and B
D. None of these

Answer

To prepare 1-methoxy-4-nitrobenzene, we can use the Williamson ether synthesis method. This involves the reaction of an alkoxide with an alkyl halide. Let's break down the steps to identify the appropriate reactants.

### Step-by-Step Solution:

1. **Identify the Desired Product**:
- We want to synthesize 1-methoxy-4-nitrobenzene. This compound has a methoxy group (-OCH3) at the 1-position and a nitro group (-NO2) at the 4-position of the benzene ring.

2. **Determine the Alkoxide Source**:
- To introduce the methoxy group, we need to use sodium methoxide (NaOCH3) as the alkoxide. This will provide the methoxy group for the final product.

3. **Choose the Alkyl Halide**:
- We need a suitable alkyl halide that can react with the alkoxide. The alkyl halide should be a primary halide to ensure a good SN2 reaction. In this case, we can use methyl chloride (CH3Cl) as the alkyl halide.

4. **Consider the Nitro Group**:
- The nitro group must be introduced at the para position (4-position) of the benzene ring. We can start with nitrobenzene (C6H5NO2) as our starting material.

5. **Perform the Williamson Ether Synthesis**:
- The reaction involves the nucleophilic attack of the methoxide ion (from NaOCH3) on the methyl chloride (CH3Cl) to form the ether. The nitro group is already present in the nitrobenzene, so we can directly use it in the reaction.

6. **Final Reaction**:
- The overall reaction can be summarized as:
- **Starting materials**: Nitrobenzene (C6H5NO2) + Sodium Methoxide (NaOCH3) + Methyl Chloride (CH3Cl)
- **Product**: 1-methoxy-4-nitrobenzene (C6H4(NO2)(OCH3))

### Conclusion:
The appropriate set of reactants for the preparation of 1-methoxy-4-nitrobenzene is:
- Nitrobenzene (C6H5NO2)
- Sodium Methoxide (NaOCH3)
- Methyl Chloride (CH3Cl)