Vitamin `B_(12)` deficiency in the body cause megakaryocytic anemia. The secretion of which of the following cells is required for the absorption of `B_(12)` ?

Options

A. Oxyntic cells
B. Neck cells
C. Chief cells
D. Crypts of Lieberkuhn

Answer

To solve the question regarding which cells are responsible for the secretion required for the absorption of Vitamin B12, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Role of Vitamin B12**:
- Vitamin B12 is essential for various bodily functions, including red blood cell formation and neurological function. Its deficiency can lead to conditions such as megakaryocytic anemia.

2. **Identify the Cells Involved in Vitamin B12 Absorption**:
- Vitamin B12 absorption primarily occurs in the ileum of the small intestine. However, it requires a specific factor for absorption.

3. **Recognize the Importance of Intrinsic Factor**:
- The intrinsic factor is a glycoprotein secreted by certain cells in the stomach. It binds to Vitamin B12 and facilitates its absorption in the intestine.

4. **Determine Which Cells Secrete Intrinsic Factor**:
- The cells responsible for secreting intrinsic factor are known as parietal cells (also referred to as oxyntic cells).

5. **Evaluate the Options Provided**:
- **Option A: Oxyntic (Parietal) Cells** - This is the correct answer as they secrete intrinsic factor necessary for Vitamin B12 absorption.
- **Option B: Neck Cells** - These cells secrete mucin and are not involved in Vitamin B12 absorption.
- **Option C: Chief Cells** - These cells produce pepsinogen, which is not related to Vitamin B12 absorption.
- **Option D: Crypts of Lieberkühn** - These are intestinal glands that secrete enzymes and mucus but do not secrete intrinsic factor.

6. **Conclude the Correct Answer**:
- Based on the analysis, the correct answer is **Option A: Oxyntic (Parietal) Cells**.

### Final Answer:
The secretion of **Oxyntic (Parietal) Cells** is required for the absorption of Vitamin B12.