Cannabinoid receptors are principle present in

Options

A. Brain
B. Bone marrow
C. Muscles
D. Gonads

Answer

### Step-by-Step Solution:

1. **Understanding Cannabinoid Receptors**: Cannabinoid receptors are specialized proteins found in the body that respond to cannabinoids, which are compounds found in cannabis and produced naturally in the body.

2. **Location of Cannabinoid Receptors**: These receptors are distributed throughout the body but are primarily concentrated in the nervous system.

3. **Function of Cannabinoid Receptors**: They play a significant role in regulating various physiological processes, including pain relief, mood regulation, and stress response.

4. **Central Role of the Brain**: The brain is the central organ where cannabinoid receptors exert their most significant effects. They help in modulating pain and stress responses, making them crucial in neurological functions.

5. **Conclusion**: Based on the information, we can conclude that cannabinoid receptors are principally present in the brain.

### Final Answer: Cannabinoid receptors are principally present in the brain.

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