Which of the following layers in the wall of uterus does not undergo cyclical changes ?

Options

A. Perimetrium only
B. Myometrium only
C. Perimetrium and Myometrium
D. Endometrium only

Answer

To solve the question "Which of the following layers in the wall of the uterus does not undergo cyclical changes?", we need to analyze the three layers of the uterus: perimetrium, myometrium, and endometrium.

### Step-by-Step Solution:

1. **Identify the Layers of the Uterus**:
- The uterus has three main layers:
- **Perimetrium**: The outermost layer, which is a thin membranous layer.
- **Myometrium**: The middle layer, composed of thick smooth muscle.
- **Endometrium**: The innermost layer, which is glandular and undergoes cyclical changes during the menstrual cycle.

2. **Understand the Function of Each Layer**:
- **Perimetrium**: This layer serves as a protective covering and does not undergo any cyclical changes related to the menstrual cycle.
- **Myometrium**: This layer is responsible for the contractions during childbirth but does not experience cyclical changes during the menstrual cycle.
- **Endometrium**: This layer is where cyclical changes occur. It thickens and sheds during the menstrual cycle in response to hormonal changes.

3. **Determine Which Layers Do Not Undergo Cyclical Changes**:
- Since the perimetrium and myometrium do not experience any cyclical changes, while the endometrium does, we can conclude that the layers that do not undergo cyclical changes are the perimetrium and myometrium.

4. **Select the Correct Answer**:
- Based on the analysis, the correct answer to the question is **C: perimetrium and myometrium**.

### Final Answer:
C: perimetrium and myometrium