DNA is a polymer of nucleotides which are linked to each other by `3'-5'` phosphodiester bond . To prevent polymerisation of nucleotides, which of the following modifications would you choose ?

Options

A. Replace purine with pyrimindines
B. Remove/ Replace 3' OH group in deoxy ribose
C. Remove/Replace2' OH group with some other group in deoxy ribose
D. Both (b) and (c)

Answer

B

Explanation

The enzhme called DNA polymerase progressively adds deoxyribonucleotides to the free 3'-end of the growing polynucleotide chain so, that replication of the 3'-5' strand of the DNA molecule is continuous (growth of the new strand in 5`to`3' direction).
replaced/removed.