In Purine nucleosides C - 1 of sugar forms glycosidic linkage with which position of purine ?

Options

A. 1
B. 3
C. 9
D. 8

Answer

To solve the question regarding the glycosidic linkage in purine nucleosides, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Purine Structure**:
- Purine is a nitrogenous base that consists of a fused double-ring structure. The two rings contain nitrogen atoms at specific positions.

2. **Identifying the Sugar**:
- In a nucleoside, the sugar is typically a ribose (in RNA) or deoxyribose (in DNA). The sugar has a carbon backbone, and we are particularly interested in the C-1 position of the sugar.

3. **Glycosidic Linkage**:
- The glycosidic linkage in nucleosides is formed between the C-1 position of the sugar and a specific position of the purine base.

4. **Numbering of Purine Positions**:
- The positions of the purine base are numbered starting from one of the nitrogen atoms in the ring structure. For purines, the numbering typically starts from the nitrogen in the 9-position.

5. **Formation of the Nucleoside**:
- In purine nucleosides, the C-1 of the sugar forms a glycosidic bond with the nitrogen atom at the 9th position of the purine base.

6. **Conclusion**:
- Therefore, in purine nucleosides, C-1 of the sugar forms a glycosidic linkage with the 9th position of the purine.

### Final Answer:
C-1 of sugar forms a glycosidic linkage with the 9th position of purine.

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