Which of the cells stay in the `G_@` phase ?

Options

A. Multinucleated muscle cells
B. Heart muscle cells
C. Neurons
D. All of these

Answer

To determine which of the cells stay in the G0 phase, we need to understand the concept of the cell cycle and the specific characteristics of the cells mentioned in the options.

### Step-by-Step Solution:

1. **Understand the Cell Cycle**: The cell cycle consists of several phases: G1, S, G2, and M. The G0 phase is a resting or quiescent stage where cells are metabolically active but do not divide.

2. **Identify the G0 Phase**: Cells that enter the G0 phase have exited the active cell cycle. They are typically differentiated cells that do not regularly undergo division.

3. **Analyze Each Option**:
- **A. Multinucleated Muscle Cells**: These cells do not undergo cytokinesis after karyokinesis, which means they can remain in the G0 phase.
- **B. Heart Muscle Cells**: Heart muscle cells (cardiomyocytes) also enter the G0 phase and do not frequently divide.
- **C. Neurons**: Neurons are highly specialized cells that generally do not divide after they have fully differentiated, thus they remain in the G0 phase.
- **D. All of These**: Since all the mentioned cell types (multinucleated muscle cells, heart muscle cells, and neurons) stay in the G0 phase, this option must be correct.

4. **Conclusion**: Since all the cell types listed (A, B, and C) remain in the G0 phase, the correct answer is **D. All of these**.

### Final Answer:
**D. All of these**

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