Glucagon characteristically increase all the following except

Options

A. protein synthesis
B. glycogenolysis
C. lipolysis in adipose tissue
D. gluconeogenesis in the liver

Answer

To solve the question regarding glucagon and its effects, we will analyze each option provided to determine which one is not increased by glucagon.

### Step-by-Step Solution:

1. **Understanding Glucagon**:
- Glucagon is a hormone produced by the alpha cells of the pancreas. It plays a crucial role in regulating blood glucose levels, especially when they are low.

2. **Analyzing the Options**:
- We need to evaluate each option to see if glucagon increases that particular process.

3. **Option 1: Protein Synthesis**:
- Glucagon does not promote protein synthesis. Instead, it focuses on increasing blood glucose levels by promoting processes like glycogenolysis and gluconeogenesis. Therefore, this option is likely the correct answer.

4. **Option 2: Glycogenolysis**:
- Glycogenolysis is the process where glycogen is broken down into glucose. Glucagon stimulates this process in the liver to increase blood glucose levels. Thus, this option is incorrect as glucagon does increase glycogenolysis.

5. **Option 3: Lipolysis in the Adipose Tissue**:
- Lipolysis is the breakdown of fats into fatty acids and glycerol. Glucagon promotes lipolysis to provide energy and increase glucose levels indirectly. Therefore, this option is also incorrect as glucagon increases lipolysis.

6. **Option 4: Gluconeogenesis in the Liver**:
- Gluconeogenesis is the synthesis of glucose from non-carbohydrate sources. Glucagon stimulates this process to raise blood glucose levels, making this option incorrect as well.

7. **Conclusion**:
- The only process that glucagon does not increase is protein synthesis. Therefore, the correct answer is **Option 1: Protein Synthesis**.

### Final Answer:
**Glucagon characteristically increases all the following except protein synthesis.**