Find the INCORRECT match.

Options

A. PCR - amplification of the gene of interest.
B. Cloning - Ability to form large number of copies of the recombinant DNA in the host cell like E. coli.
C. Restriction enzymes - Molecular scissors
D. Exonucleases - Molecular glue

Answer

To find the INCORRECT match among the given options, we need to analyze each option carefully:

### Step-by-Step Solution:

1. **Option A: PCR amplification of gene of interest**
- **Explanation**: PCR stands for Polymerase Chain Reaction. It is a technique used to amplify (make multiple copies of) a specific segment of DNA. Therefore, this option is correctly matched.
- **Conclusion**: This is a correct match.

2. **Option B: Cloning ability to form large number of copies of the recombinant DNA in the host cell like E. coli**
- **Explanation**: Cloning involves creating copies of DNA, and it is indeed used to produce large numbers of copies of recombinant DNA within a host organism, such as E. coli. Thus, this option is also correctly matched.
- **Conclusion**: This is a correct match.

3. **Option C: Restriction enzymes molecular scissors**
- **Explanation**: Restriction enzymes are indeed referred to as "molecular scissors" because they cut DNA at specific sequences. Therefore, this option is correctly matched as well.
- **Conclusion**: This is a correct match.

4. **Option D: Exonucleases molecular glue**
- **Explanation**: Exonucleases are enzymes that remove nucleotide units from the ends of a DNA molecule. They do not act as "molecular glue." Instead, molecular glue would refer to enzymes that join DNA fragments, such as ligases. Therefore, this option is incorrectly matched.
- **Conclusion**: This is an incorrect match.

### Final Answer:
The INCORRECT match is **Option D: Exonucleases Molecular Glue**.