Find out the correctly matched option of the causative agent and their disease.

Options

A. Prion-Bovine Spongiform Encephalopathy
B. Virus - Citrus Canker disease
C. Viroids - Cr- Jacob disease in human
D. Bacteria- small pox

Answer

To solve the question of finding the correctly matched option of the causative agent and their disease, we will analyze each option provided.

### Step-by-Step Solution:

1. **Identify the Causative Agents and Diseases:**
- The question provides pairs of causative agents and diseases. We need to evaluate each pair to determine if they are correctly matched.

2. **Option 1: Pyrons and Bovine Spongiform Encephalopathy (BSE)**
- Pyrons are infectious agents that cause neurological diseases. Bovine Spongiform Encephalopathy (BSE), commonly known as Mad Cow Disease, is indeed caused by pyrons.
- **Conclusion:** This option is correctly matched.

3. **Option 2: Virus and Citrus Canker Disease**
- Citrus Canker Disease is caused by a bacterium called Xanthomonas citri, not a virus. Therefore, this option is incorrectly matched.
- **Conclusion:** This option is incorrectly matched.

4. **Option 3: C.R. Jockup Disease in Humans and Bacteria**
- C.R. Jockup Disease (more commonly known as Creutzfeldt-Jakob Disease) is also caused by pyrons, not bacteria. Hence, this option is incorrectly matched.
- **Conclusion:** This option is incorrectly matched.

5. **Option 4: Smallpox and Virus**
- Smallpox is a viral disease caused by the variola virus. This matches correctly with the causative agent being a virus.
- **Conclusion:** This option is correctly matched.

### Final Conclusion:
The correctly matched options are:
- Option 1: Pyrons and Bovine Spongiform Encephalopathy (BSE)
- Option 4: Virus and Smallpox