In prophase I, the stage that closely resembles prometaphase of mitosis is :

Options

A. Diplotene
B. Chaismata
C. Leptotene
D. Diakinesis

Answer

To solve the question, "In prophase I, the stage that closely resembles prometaphase of mitosis is:", we need to analyze the stages of prophase I and their characteristics in relation to prometaphase of mitosis.

### Step-by-Step Solution:

1. **Understanding Prophase I**: Prophase I of meiosis consists of five stages: Leptotene, Zygotene, Pachytene, Diplotene, and Diakinesis. Each stage has distinct characteristics.

2. **Characteristics of Prometaphase**: In prometaphase of mitosis, the nuclear envelope breaks down, allowing spindle fibers to attach to the kinetochores of the chromosomes. This is a crucial step for proper chromosome alignment and segregation.

3. **Analyzing Each Stage of Prophase I**:
- **Leptotene**: Chromosomes begin to condense but the nuclear envelope is still intact.
- **Zygotene**: Homologous chromosomes begin to pair (synapsis), but again, the nuclear envelope has not broken down.
- **Pachytene**: Chromosomes are fully paired, and crossing over occurs, but the nuclear envelope is still present.
- **Diplotene**: Homologous chromosomes begin to separate slightly, but the nuclear envelope remains intact.
- **Diakinesis**: The chromosomes become maximally condensed, the nuclear envelope breaks down, and the nucleolus disappears. This stage closely resembles the prometaphase of mitosis because the nuclear envelope breakdown allows spindle fibers to attach to the kinetochores.

4. **Conclusion**: Based on the analysis, the stage of prophase I that closely resembles prometaphase of mitosis is **Diakinesis**.

### Final Answer:
**Diakinesis** is the stage in prophase I that closely resembles prometaphase of mitosis.