The hormone which suppresses the immune system is produce by

Options

A. zona fasciculata of adrenal cortex
B. zona glomerulosa of adrenal cortex
C. zona reticular's of adrenal cortex
D. Both (A) and (C )

Answer

To solve the question regarding which hormone suppresses the immune system and where it is produced, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Hormone**: The hormone that suppresses the immune system is cortisol. It is a glucocorticoid hormone.

**Hint**: Remember that glucocorticoids are primarily involved in stress response and immune regulation.

2. **Understand the Function of Cortisol**: Cortisol has several functions, including increasing blood glucose levels, reducing inflammation, and suppressing the immune response.

**Hint**: Think about how cortisol is often associated with stress and its role in managing inflammation.

3. **Locate the Source of Production**: Cortisol is produced in the adrenal glands, specifically in the adrenal cortex.

**Hint**: Recall the structure of the adrenal glands and their division into cortex and medulla.

4. **Identify the Layers of the Adrenal Cortex**: The adrenal cortex is divided into three layers:
- Zona Glomerulosa (produces mineralocorticoids like aldosterone)
- Zona Fasciculata (produces glucocorticoids like cortisol)
- Zona Reticularis (produces sex corticoids)

**Hint**: Remember the order of the layers from outer to inner and their respective hormone production.

5. **Determine the Correct Layer for Cortisol**: Since cortisol is produced in the Zona Fasciculata, this is the correct layer of the adrenal cortex responsible for producing the hormone that suppresses the immune system.

**Hint**: Focus on the middle layer of the adrenal cortex when thinking about glucocorticoids.

6. **Conclusion**: Therefore, the hormone that suppresses the immune system is produced by the Zona Fasciculata of the adrenal cortex.

**Hint**: Summarize your findings by linking the hormone to its specific layer in the adrenal cortex.

### Final Answer:
The hormone which suppresses the immune system is produced by the Zona Fasciculata of the adrenal cortex.