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Assertion: Primary transcripts in eukary...

Assertion: Primary transcripts in eukaryotes are nonfunctional.
Reason: Methyl guanosine triphosphate is attached to 5' - end of hnRNA.

A

Both assertion and reason are true, and reason is the correct explanation of assertion.

B

Both assertion and reason are true, but reason is not the correct explanation of assertion.

C

Assertion is true but reason is false.

D

Both assertion and reason are false.

Text Solution

AI Generated Solution

The correct Answer is:
To solve the question regarding the assertion and reason, we will analyze both statements step by step. ### Step 1: Analyze the Assertion **Assertion:** Primary transcripts in eukaryotes are nonfunctional. - In eukaryotic cells, the primary transcript (also known as heterogeneous nuclear RNA or hnRNA) is synthesized from DNA during transcription. - This primary transcript contains both exons (coding sequences) and introns (non-coding sequences). - Because it contains introns, which need to be removed through a process called splicing, the primary transcript is not yet functional as mRNA. Therefore, the assertion is true. ### Step 2: Analyze the Reason **Reason:** Methyl guanosine triphosphate is attached to the 5' end of hnRNA. - The primary transcript (hnRNA) undergoes several modifications before it becomes a functional mRNA. - One of these modifications is the addition of a 5' cap, which is indeed a methyl guanosine triphosphate (m7G) cap. - This capping is crucial for mRNA stability and for the initiation of translation. Therefore, the reason is also true. ### Step 3: Determine the Relationship Between Assertion and Reason - The assertion states that primary transcripts are nonfunctional, which is correct because they contain introns that need to be spliced out. - The reason correctly describes a modification (5' capping) that occurs in hnRNA, but it does not explain why the primary transcript is nonfunctional. The reason is true, but it does not provide a direct explanation for the assertion. ### Conclusion Based on the analysis: - Both the assertion and the reason are true. - However, the reason is not the correct explanation of the assertion. Thus, the correct answer is: **Assertion and reason are true, but the reason is not the correct explanation of the assertion.**

To solve the question regarding the assertion and reason, we will analyze both statements step by step. ### Step 1: Analyze the Assertion **Assertion:** Primary transcripts in eukaryotes are nonfunctional. - In eukaryotic cells, the primary transcript (also known as heterogeneous nuclear RNA or hnRNA) is synthesized from DNA during transcription. - This primary transcript contains both exons (coding sequences) and introns (non-coding sequences). - Because it contains introns, which need to be removed through a process called splicing, the primary transcript is not yet functional as mRNA. Therefore, the assertion is true. ...
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