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The genomic content of the nucleus is co...

The genomic content of the nucleus is constant for a given species where as the extrachromosomal DNA is found to be variable among the members of a population. Explain.

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The genomic content of nucleus is species specific e.g. 23 pairs of chromosomes in all the human beings of the world. It is related to hereditary informations. Each chromosome has a specific number of genes present linearly in the specific sequence. This species specific genomic content is maintained by its duplication in S-phase followed by its specific arrangement and separation during M-phase of the cell cycle. Loss of any chromosome causes loss of many genes which is generally fatal.
But the content of extra -chromosomal DNA is not species specific as its doubling and separation is a random process and may or may not occur. The genes of extra-genomic DNA are not so vital for the survival of organism.
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