Excessive secretion of somatotropin leads to a disorder called :
(1) Gigantism
(2) Acromegaly
(3) Cretinism
(4) Addison's disease

Options

A. 1,2 and 3 are correct
B. 1 and 2 are correct
C. 2 and 4 are correct
D. 1 and 3 are correct

Explanation

To solve the question regarding the disorder caused by excessive secretion of somatotropin (growth hormone), we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Somatotropin**:
- Somatotropin is also known as growth hormone (GH). It is produced by the pituitary gland and is responsible for growth and development in children and adolescents.

2. **Identifying the Effects of Excessive Somatotropin**:
- Excessive secretion of somatotropin can lead to different disorders depending on the age of onset.
- In children, excessive growth hormone leads to **Gigantism**, characterized by excessive growth and height.
- In adults, excessive growth hormone leads to **Acromegaly**, which is characterized by the enlargement of bones and tissues, particularly in the hands, feet, and face.

3. **Analyzing the Options**:
- **(1) Gigantism**: Correct for excessive somatotropin in children.
- **(2) Acromegaly**: Correct for excessive somatotropin in adults.
- **(3) Cretinism**: Incorrect; this is related to thyroid hormone deficiency, not somatotropin.
- **(4) Addison's disease**: Incorrect; this involves adrenal hormone deficiency, not somatotropin.

4. **Conclusion**:
- Since both Gigantism and Acromegaly are associated with excessive secretion of somatotropin, the correct answer to the question is **(2) Acromegaly** as it is specifically mentioned in the context of excessive secretion in adults.

### Final Answer:
The disorder caused by excessive secretion of somatotropin is **(2) Acromegaly**.

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