Which of the following statements is incorrect?

Options

A. Enzymes are organic catalysts.
B. Enzymes have a very large turnover number.
C. Enzymes action is specific.
D. Enzymes always require a coenzyme in their catalytic action.

Explanation

To determine which statement is incorrect, let's analyze each option one by one:

### Step 1: Analyze Statement A
**Statement A:** "Enzymes are Organic Catalysts."
- Enzymes are indeed organic catalysts, primarily made of proteins, which catalyze biochemical reactions in living organisms.
- **Conclusion:** This statement is **correct**.

### Step 2: Analyze Statement B
**Statement B:** "Enzymes have very large turnover number."
- The turnover number refers to the number of substrate molecules converted to product by an enzyme per unit time. Many enzymes, such as catalase, have a very high turnover number.
- **Conclusion:** This statement is **correct**.

### Step 3: Analyze Statement C
**Statement C:** "Enzyme's action is specific."
- Enzymes are known for their specificity; for example, maltase specifically catalyzes the hydrolysis of maltose into glucose.
- **Conclusion:** This statement is **correct**.

### Step 4: Analyze Statement D
**Statement D:** "Enzyme always requires a coenzyme in their catalytic action."
- While some enzymes require coenzymes to be active (these are called apoenzymes), there are many enzymes that do not require coenzymes (e.g., maltase). Therefore, the statement that enzymes "always" require a coenzyme is incorrect.
- **Conclusion:** This statement is **incorrect**.

### Final Answer
The incorrect statement is **Statement D**: "Enzyme always requires a coenzyme in their catalytic action."

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