What is the effect of denaturation on the structure of proteins?

Explanation

### Step-by-Step Text Solution:

1. **Definition of Denaturation**: Denaturation refers to the process where a protein loses its native structure due to the disruption of various interactions that maintain its shape. This can be caused by factors such as heat, pH changes, or chemical agents.

2. **Impact on Protein Structure**: During denaturation, the secondary and tertiary structures of the protein are primarily affected. These structures are held together by various interactions, including hydrogen bonds, ionic bonds, and hydrophobic interactions.

3. **Destruction of Secondary and Tertiary Structures**: The secondary structure, which includes alpha helices and beta sheets, and the tertiary structure, which refers to the overall three-dimensional shape of the protein, are disrupted. This leads to the unfolding of the protein.

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