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Glutamic acid, H(2)N-CH(CH(2)CH(2)COOH)C...

Glutamic acid, `H_(2)N-CH(CH_(2)CH_(2)COOH)COOH` has `pK_(a1),(alpha-COOH)=2.2, pK_(a2)(alpha-overset(+)(N)H_(3))=9.8` and `pK_(a3)` (R group COOH) = 4.3. The isoelectric point of glutamic acid is

A

`5.9`

B

7

C

`10.2`

D

`3.25`

Text Solution

Verified by Experts

The correct Answer is:
D
Acidic amino acid `p_(1)=(1)/(2)[p^(Ka_(2))+p^(Ka_(3))]=(1)/(2)[2.2+4.3]=3.25`
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AAKASH SERIES-PROTEINS AND NUCLEIC ACIDS -LEVEL - II LECTURE SHEET (EXERCISE - I)
  1. The pH value of a solution in which a polar amino acid doesn't migrate...

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  2. The structural feature which distinguishes proline from alpha - amino ...

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  3. Which amino acid is achiral ?

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  4. Which is not a true statement ?

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  5. Which of the following structure represents the peptide chain ?

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  6. All common amino acids except one react with cold nitrous acid (HNO(2)...

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  7. The amino acid cysteine often forms a disulphide bond with another nea...

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  8. Peptides on hydrolysis gives

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  9. Peptides are composed of amino acids joined by amide bonds. Which of t...

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  10. Which of the following is used in a colour test of amino acid ?

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  11. Isoelectric point is

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  12. Histidine has pK(a1)=1.8, pK(a2)=09.2 and pK(a3)=6.0. The isoelectric ...

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  13. Glutamic acid, H(2)N-CH(CH(2)CH(2)COOH)COOH has pK(a1),(alpha-COOH)=2....

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  14. Which of the following is the major solute species in a solution of ly...

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  15. In an electric field, if an amino acid migrates towards cathode, the p...

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  16. During the process of digestion, the proteins present in food material...

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  17. The helical structure or a secondary structure of proteins is stabilis...

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  18. Proteins give

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  19. The destruction of the biological nature and activity of proteins by h...

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  20. The primary structure of protein is based upon the

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