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The glomerular filtrate in the loop of H...

The glomerular filtrate in the loop of Henle gets concentrated in the descending and then gets diluted in the ascending limbs. Explain.

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**Step-by-Step Solution:** 1. **Understanding the Structure of the Loop of Henle:** - The Loop of Henle consists of two main parts: the descending limb and the ascending limb. Each limb has different permeabilities to water and solutes. 2. **Concentration in the Descending Limb:** - The descending limb of the Loop of Henle has thin walls that are permeable to water but not to solutes. - As the glomerular filtrate moves down the descending limb, it encounters an increasing osmolarity in the surrounding medullary interstitium (the tissue surrounding the nephron). ...
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Assertion: In the descending limb of loop of Henle the urine is hypotonic, while in ascending limb of loop of Henle, the urine is hypertonic. Reason: Descending limb is impermeable to water while ascending limb is impermeable to Na^(+)

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