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The best reagent for converting 2-phenyl...

The best reagent for converting 2-phenylpropanamide into 2-phenylpropanamine is….

A

excess H2

B

`Br_(2)` in aqueous NaOH

C

iodine in the presence of red phosphorus

D

`LiAlH_(4)` in ether

Text Solution

AI Generated Solution

The correct Answer is:
To convert 2-phenylpropanamide into 2-phenylpropanamine, we need to remove the carbonyl group (C=O) from the amide functional group (–C(=O)NH2) and replace it with an amine (–NH2) group. The best reagent for this transformation is lithium aluminum hydride (LiAlH4) in ether. Here’s the step-by-step solution: ### Step 1: Identify the Functional Groups - **Starting Compound**: 2-phenylpropanamide (C6H5-CH(CH3)-C(=O)-NH2) - **Target Compound**: 2-phenylpropanamine (C6H5-CH(CH3)-NH2) ### Step 2: Understand the Reaction - The reaction involves the reduction of the amide group to an amine group. This means we need to convert the carbonyl (C=O) of the amide into an amine (–NH2). ### Step 3: Choose the Reagent - The best reagent for this conversion is lithium aluminum hydride (LiAlH4). This reagent is a strong reducing agent that can effectively reduce the carbonyl group in amides to amines. ### Step 4: Set Up the Reaction Conditions - The reaction should be carried out in an ether solvent, which is suitable for the lithium aluminum hydride to dissolve and react with the amide. ### Step 5: Perform the Reaction - Add lithium aluminum hydride to the 2-phenylpropanamide in an ether solvent. The LiAlH4 will donate hydride ions (H-) to the carbonyl carbon, effectively reducing it to an amine. ### Step 6: Work Up the Reaction - After the reaction is complete, quench the reaction mixture with water or a dilute acid to destroy any excess LiAlH4 and to protonate the amine product. ### Step 7: Isolate the Product - Finally, isolate the 2-phenylpropanamine from the reaction mixture, typically through extraction and purification techniques. ### Final Answer The best reagent for converting 2-phenylpropanamide into 2-phenylpropanamine is lithium aluminum hydride (LiAlH4) in ether. ---

To convert 2-phenylpropanamide into 2-phenylpropanamine, we need to remove the carbonyl group (C=O) from the amide functional group (–C(=O)NH2) and replace it with an amine (–NH2) group. The best reagent for this transformation is lithium aluminum hydride (LiAlH4) in ether. Here’s the step-by-step solution: ### Step 1: Identify the Functional Groups - **Starting Compound**: 2-phenylpropanamide (C6H5-CH(CH3)-C(=O)-NH2) - **Target Compound**: 2-phenylpropanamine (C6H5-CH(CH3)-NH2) ### Step 2: Understand the Reaction - The reaction involves the reduction of the amide group to an amine group. This means we need to convert the carbonyl (C=O) of the amide into an amine (–NH2). ...
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