Acid anhydrides on reaction with primary amine gives…

Options

A. amide
B. imide
C. secondary amine
D. imine

Explanation

To solve the question "Acid anhydrides on reaction with primary amine gives…", we will follow these steps:

### Step-by-Step Solution:

1. **Identify the Reactants**:
- We have an acid anhydride, which can be represented as \( RCO - O - CO - R \) or simply \( (RCO)_2O \).
- We also have a primary amine, represented as \( R'NH_2 \).

2. **Understand the Reaction Mechanism**:
- The primary amine has a lone pair of electrons on the nitrogen atom, which allows it to act as a nucleophile.
- The carbonyl carbon in the acid anhydride is electrophilic due to the presence of the electronegative oxygen atoms.

3. **Nucleophilic Attack**:
- The nitrogen from the primary amine attacks the electrophilic carbon of the acid anhydride, resulting in the formation of a tetrahedral intermediate.
- This intermediate can be represented as \( RCO - O - C^+(R) - NH_2(R') \).

4. **Formation of Amide**:
- The tetrahedral intermediate rearranges, leading to the departure of one of the acyl groups as a good leaving group (which is the acetate ion, \( RCOO^- \)).
- This results in the formation of an amide, represented as \( RCONHR' \).

5. **Final Product**:
- The final product of the reaction is an amide \( RCONHR' \) and the by-product is the acetate ion \( RCOO^- \).

### Conclusion:
The reaction of acid anhydrides with primary amines produces **amide** as the major product.

### Answer:
**Amide**

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