How does the process of natural selection affect Hardy-Weinberg equilibrium? Explain List the other four factors that disturb the equilibrium.

Explanation

### Step-by-Step Solution:

1. **Understanding Hardy-Weinberg Equilibrium**:
- The Hardy-Weinberg principle states that in a large population, the allele frequencies and genotype frequencies remain constant from generation to generation, provided that certain conditions are met. The total gene pool remains stable, and the sum of all allele frequencies equals 1.

2. **Impact of Natural Selection**:
- Natural selection is a process where individuals with favorable traits are more likely to survive and reproduce. This leads to a change in allele frequencies in the population over time.
- When natural selection occurs, it favors certain traits that are better adapted to the environment. As a result, the allele frequencies change, which contradicts the Hardy-Weinberg principle that states allele frequencies should remain constant.
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