Mention the chemical change that proinsulin undergoes to be able to act as mature insulin

Explanation

To transform proinsulin into mature insulin, the following chemical change occurs:

1. **Removal of the C Chain**: Proinsulin is synthesized as an inactive precursor that contains an additional peptide chain known as the C chain. This chain is not present in the mature insulin form and prevents proinsulin from being fully functional.

2. **Formation of Disulfide Bridges**: After the C chain is cleaved off, the remaining A and B polypeptide chains are linked together by disulfide bonds (also known as disulfide bridges). These covalent bonds stabilize the structure of the mature insulin molecule.

3. **Resulting Structure of Mature Insulin**: The final product, mature insulin, consists of two polypeptide chains (A and B) that are connected by disulfide bridges, allowing it to perform its biological function effectively.

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