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A relevant portion of beta-chain of haem...

A relevant portion of `beta`-chain of haemoglobin of a normal human is given below :

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Due to mutation A , GAG mutates to GAA. Both GAG and GAA code for glutamic acid and hence there is no change in RBCs. Whereas GUG formed due to mutation B codes for valine and so the RBCs become sickle-shaped.
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Given below is the representation of amino acid composition of the relevant translated portion of beta -chain of haemoglobin, related to the shape of human red blood cells. (a) Is this representation indicating a normal human or a sufferer from certain related genetic disease? Give reason in support of your answer. (b) What difference would be noticed in the phenotype of the normal and the sufferer related to this gene? (c) Who are likely to suffer more from the defect related to the gene represented the males, the females or both males and females equally? And why?

Given below is the representation of amino acid composition of the relevant translated portion of beta -chain of haemoglobin, related to the shape of human red blood cells. (a) Is this representation indicating a normal human or a sufferer from certain related genetic disease? Give reason in support of your answer. (b) What difference would be noticed in the phenotype of the normal and the sufferer related to this gene? (c) Who are likely to suffer more from the defect related to the gene represented the males, the females or both males and females equally? And why?

Given below is the representation of a relevant part of amino acid composition of the beta -chain of haemoglobin, related to the shape of human red blood cells. (a) Is this representation of the sequence of amino acids indicating a normal human or a sufferer from a certain blood related genetic disease ? Give reason in support of your answer. (b) Why is the disease referred to as a Mendelian disorder ? Explain.

Which one of the following is correct for a normal human?

Human haemoglobin is made up of

Which is correct in normal humans

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