Haemoglobin breakdown occurs in

Options

A. Liver
B. Kidney
C. Lungs
D. Heart

Answer

### Step-by-Step Solution:

1. **Understanding Hemoglobin Breakdown**:
- Hemoglobin is a protein found in red blood cells (RBCs) that carries oxygen. When RBCs reach the end of their lifespan, hemoglobin needs to be broken down.

2. **Location of Breakdown**:
- The breakdown of hemoglobin primarily occurs in the **liver**. This organ is responsible for processing and detoxifying various substances, including the breakdown products of hemoglobin.

3. **Process of Breakdown**:
- Hemoglobin is broken down into two main components: **heme** and **globin**.
- **Globin**: This is the protein part of hemoglobin and is further broken down into amino acids.
- **Heme**: This is the iron-containing component. It undergoes further breakdown.

4. **Further Breakdown of Heme**:
- The heme group is converted into **biliverdin**, which is a green pigment.
- Biliverdin is then converted into **bilirubin**, an orange pigment.

5. **Final Product**:
- The end product of hemoglobin breakdown is **bilirubin**, which is a brownish-yellow bile pigment.
- Approximately 80% of bilirubin is produced from the degradation of erythrocyte hemoglobin.

6. **Role of Bilirubin**:
- Bilirubin is secreted by the liver and contributes to the color of bile and feces, indicating the breakdown of red blood cells.

### Conclusion:
The correct answer to the question "Hemoglobin breakdown occurs in" is **liver**.

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