(i) List the chromosomal disorders a human may suffer from if karyotype analysis of the individual shows 47 chromosomes instead of normal 46
(ii) Explain the cause that results in the gain of chromosome number.
(iii) Mention the symptoms of any one the disorders an individual can suffer from

Explanation

(i)Down's syndrome: Edward's syndrome: Patau's syndrome: Klinefelter's syndrome: Super Female: Super Male
(ii) All these disorders result due to nondisjunction
(iii) Klinefelter's Syndrome. Klinefelter's syndrome is due to trisomy of sex (X) chromosome. It is formed by the union of an abnormal XX egg and normal Y sperm or normal X egg and abnormal XY sperm. The individual has 47 chromosomes (44+XXY). Such persons are sterile males (called feminised male) with undeveloped testes, mental retardation female like sparse body hair and knock knees. long limbs and with some female characteristics such as feminine pitched voice and enlarged breasts (gynaecomastia). It is considered that the more the X chromosomes the greater is the mental defect