A Bioactive molecule, Cyclosporin-A used as an immuno-suppressive agent in organ- transplant patients is produced by

Options

A. Aspergillus niger
B. Saccharomyces cerevisiae
C. Monascus purpurens
D. Trichoderma polysporum

Explanation

**Step-by-Step Solution:**

1. **Understanding the Context of Cyclosporin-A**: Cyclosporin-A is a bioactive molecule that serves as an immunosuppressive agent, particularly in organ transplant patients. It is crucial for preventing the rejection of transplanted organs by the recipient's immune system.

2. **Identifying the Problem of Organ Transplantation**: When an organ is transplanted from one person to another, the recipient's immune system may recognize the new organ as foreign. This is primarily due to the action of T lymphocytes, which are part of the immune response.

3. **Role of Immunosuppressants**: To prevent the rejection of the transplanted organ, immunosuppressive drugs like Cyclosporin-A are administered. These drugs help to suppress the immune response, allowing the transplanted organ to function without being attacked by the recipient's immune system.

4. **Source of Cyclosporin-A**: Cyclosporin-A is derived from a specific type of fungus. The question asks for the organism that produces this bioactive molecule.

5. **Evaluating Options**:
- **Aspergillus niger**: This is a fungus but is not known for producing Cyclosporin-A.
- **Saccharomyces cerevisiae**: This yeast is primarily used in baking and brewing, not for producing Cyclosporin-A.
- **Monascus purpureus**: This fungus is known for producing statins, which are cholesterol-lowering drugs, not Cyclosporin-A.
- **Trichoderma polysporum**: This is the correct fungus that produces Cyclosporin-A.

6. **Conclusion**: The correct answer to the question is that Cyclosporin-A is produced by **Trichoderma polysporum**.

**Final Answer**: Cyclosporin-A is produced by **Trichoderma polysporum**.

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