In a mammalian kidney, loops of Henle are mainly located in

Options

A. pelvis
B. cortex
C. medulla
D. major calyx

Answer

To determine where the loops of Henle are mainly located in a mammalian kidney, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Structure of the Kidney**: The mammalian kidney consists of two main regions: the cortex and the medulla. The cortex is the outer layer, while the medulla is the inner layer.

2. **Identify the Nephron Components**: The nephron, which is the functional unit of the kidney, includes several parts: Bowman's capsule, glomerulus, proximal convoluted tubule (PCT), loop of Henle, distal convoluted tubule (DCT), and collecting duct.

3. **Locate the Loop of Henle**: The loop of Henle is a U-shaped structure that connects the PCT and DCT. It has a descending limb and an ascending limb.

4. **Determine the Location of the Loop of Henle**: The loop of Henle primarily extends into the medulla of the kidney. This is where the concentration of salts occurs, which is crucial for the kidney's ability to concentrate urine.

5. **Choose the Correct Answer**: Based on the information gathered, the loops of Henle are mainly located in the medulla of the kidney. Therefore, the correct answer to the question is option C: medulla.

### Final Answer:
The loops of Henle are mainly located in the **medulla** of the mammalian kidney (Option C).

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