Diabetes insipidus is due to

Options

A. excess of insulin
B. deficiency of insulin
C. hyposecretion of hypothalamic hormone
D. hypersecretion of pituitary hormone

Answer

**Step-by-Step Solution:**

1. **Understanding Diabetes Insipidus:**
- Diabetes insipidus is a condition characterized by excessive thirst and the excretion of large amounts of dilute urine. It is important to understand the underlying causes of this condition.

2. **Identifying the Hormones Involved:**
- The key hormone involved in regulating water balance in the body is Antidiuretic Hormone (ADH), also known as vasopressin. It is synthesized in the hypothalamus and stored in the posterior pituitary gland.

3. **Recognizing the Cause of Diabetes Insipidus:**
- Diabetes insipidus is primarily caused by a deficiency of ADH. This deficiency can arise from two main issues:
- Hyposecretion (reduced secretion) of ADH from the posterior pituitary.
- Insensitivity of the kidneys to the effects of ADH.

4. **Conclusion:**
- The correct answer to the question "Diabetes insipidus is due to" is **hyposecretion of hypothalamic hormone**, specifically the hyposecretion of ADH.