Consider the following four statements (i-iv) regarding kidney transplant and select the two correct ones out of these
(i) Even if a kidney transplant is proper the recipient may need to take immuno-suppressants for a long time
(ii) The cell-mediated immune response is responsible for the graft rejection
(iii) The B-lumphocytes are responsible for rejection of the graft
(iv) The acceptance or rejection of a kidney transplant depends on specific interferons
The correct statements are

Options

A. (i) and (ii)
B. (ii) and (iii)
C. (iii) and (iv)
D. (i) and (ii)

Answer

To solve the question regarding the correct statements about kidney transplants, we will analyze each statement one by one.

### Step-by-Step Solution:

1. **Statement (i)**: "Even if a kidney transplant is proper, the recipient may need to take immuno-suppressants for a long time."
- **Analysis**: This statement is true. After a kidney transplant, the recipient's immune system may recognize the new kidney as foreign and attack it. To prevent this, immuno-suppressant drugs are prescribed to help the body accept the transplanted organ. This treatment often continues for the lifetime of the recipient.

2. **Statement (ii)**: "The cell-mediated immune response is responsible for the graft rejection."
- **Analysis**: This statement is also true. The cell-mediated immune response, primarily involving T-cells, plays a significant role in the rejection of transplanted organs (grafts). T-cells recognize the foreign antigens on the transplanted kidney and initiate an immune response against it.

3. **Statement (iii)**: "The B-lymphocytes are responsible for rejection of the graft."
- **Analysis**: This statement is false. While B-lymphocytes are involved in the immune response, they primarily produce antibodies and are not the main players in graft rejection. The rejection process is mainly mediated by T-cells (cell-mediated immunity).

4. **Statement (iv)**: "The acceptance or rejection of a kidney transplant depends on specific interferons."
- **Analysis**: This statement is also false. While interferons are involved in immune responses, the acceptance or rejection of a transplant is not primarily dependent on them. Instead, it is more about the recognition of foreign antigens by T-cells.

### Conclusion:
The two correct statements regarding kidney transplants are:
- **(i)**: Even if a kidney transplant is proper, the recipient may need to take immuno-suppressants for a long time.
- **(ii)**: The cell-mediated immune response is responsible for the graft rejection.

Thus, the correct answer is **(i) and (ii)**.