Lysosomes are never involved in

Options

A. Autophagy
B. Extracellular digestion
C. Intracellular digestion
D. Synthesis of lysosomal enzymes

Answer

**Step-by-Step Solution:**

1. **Understanding Lysosomes**: Begin by defining what lysosomes are. Lysosomes are membrane-bound organelles that contain hydrolytic enzymes responsible for breaking down waste materials and cellular debris.

2. **Functions of Lysosomes**: Identify the key functions of lysosomes. They are involved in:
- **Autophagy**: The process where lysosomes digest the cell's own components, such as damaged organelles.
- **Extracellular Digestion**: The breakdown of materials outside the cell.
- **Intracellular Digestion**: The digestion of materials within the cell.

3. **Enzymatic Activity**: Note that lysosomes contain about 60 different hydrolytic enzymes, which facilitate the digestion of various biomolecules, including lipids, proteins, and nucleic acids.

4. **Synthesis of Lysosomal Enzymes**: Understand where lysosomal enzymes are synthesized. The synthesis occurs in the endoplasmic reticulum (ER), and after synthesis, these enzymes are transported to the Golgi apparatus for further processing before being sent to the lysosomes.

5. **Identifying the Incorrect Statement**: The question asks which process lysosomes are never involved in. Since lysosomes perform autophagy, extracellular digestion, and intracellular digestion, the only option that does not involve lysosomes is the synthesis of lysosomal enzymes.

6. **Conclusion**: Therefore, the correct answer is that lysosomes are never involved in the synthesis of lysosomal enzymes.

**Final Answer**: Lysosomes are never involved in the synthesis of lysosomal enzymes.

---