Genetically engineered human insulin is synthesized with the help of

Options

A. Rhizopus
B. Rabbit/Guinea pig
C. E. coli
D. Pseudomonas

Answer

**Step-by-Step Solution:**

1. **Understanding Insulin's Role**: Insulin is a hormone produced by the pancreas that helps regulate blood sugar levels in the body. When blood sugar levels rise, insulin is released to help lower them.

2. **Genetic Engineering Context**: Genetically engineered insulin refers to insulin that is produced through biotechnological methods rather than being extracted from the pancreas of animals or humans.

3. **Gene of Interest**: The gene responsible for producing human insulin is identified and extracted. This gene is referred to as the "gene of interest."

4. **Choosing a Host Organism**: The extracted insulin gene is inserted into a suitable host organism that can produce the insulin protein. In this case, the host organism is *E. coli* (Escherichia coli), a type of bacteria commonly used in biotechnology for protein production.

5. **Transformation Process**: The *E. coli* bacteria are transformed with the insulin gene, allowing them to produce the insulin protein as they grow and reproduce.

6. **Harvesting Insulin**: After the *E. coli* have multiplied, the insulin protein is extracted and purified from the bacterial culture.

7. **Final Product**: The purified insulin is then formulated into injections for use by diabetic patients to help manage their blood sugar levels.

8. **Conclusion**: Therefore, the genetically engineered human insulin is synthesized with the help of *E. coli*.

**Final Answer**: E. coli

---