Besides better aeration and mixing property what other advantages do stirred tank bioreactors have over shake flasks?

Explanation

**Step-by-Step Text Solution:**

1. **Introduction to Stirred Tank Bioreactors (STBRs)**: Stirred tank bioreactors are commonly used for culturing biological agents like cells, enzymes, or antibodies. They utilize internal mechanical agitation to ensure proper mixing and aeration within the reactor.

2. **Large Scale Culture Preparation**: One of the primary advantages of stirred tank bioreactors over shake flasks is their ability to prepare cultures on a large scale. This is essential for industrial applications where bulk quantities of biological products are required.

3. **Withdrawal of Culture Samples**: Stirred tank bioreactors allow for the withdrawal of small volumes of culture without disrupting the overall system. This feature is crucial for sampling, testing, and monitoring the culture's progress.

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