In context of amniocentesis, which of the following statement is incorrect?

Options

A. It can be used for detection of Down syndrome.
B. It can be used for detection of cleft palate.
C. It is usually done when a woman is between 14 - 16 week pregnant.
D. It is used for prenatal sex determination.

Answer

### Step-by-Step Solution:

1. **Understanding Amniocentesis**:
- Amniocentesis is a medical procedure used during pregnancy to extract amniotic fluid. This fluid surrounds the fetus and contains fetal cells.

2. **Procedure Timing**:
- The procedure is typically performed between the 14th and 16th week of pregnancy. This timing is important for the accuracy of the test and the safety of the fetus.

3. **Purpose of Amniocentesis**:
- The primary purposes of amniocentesis include:
- Detecting chromosomal abnormalities (e.g., Down syndrome).
- Determining the sex of the fetus.
- Assessing certain genetic conditions.

4. **Evaluating the Statements**:
- Now, we need to evaluate the given statements to identify which one is incorrect:
- **Statement A**: "Amniocentesis is usually done when a woman is 14 to 16 weeks pregnant." (Correct)
- **Statement B**: "Amniocentesis is useful for the detection of cleft palate." (Incorrect)
- **Statement C**: "Amniocentesis can be used for sex determination of the fetus." (Correct)
- **Statement D**: "Amniocentesis is used for the detection of Down syndrome." (Correct)

5. **Identifying the Incorrect Statement**:
- Among the statements, Statement B is incorrect because cleft palate is not typically detectable through amniocentesis. Cleft palate is influenced by both genetic and environmental factors, making it unsuitable for detection via this procedure.

6. **Conclusion**:
- Therefore, the incorrect statement in the context of amniocentesis is **Statement B**.