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Which of the following reactions(s) is/a...

Which of the following reactions(s) is/are sterospecific but non-steroselcetive?

A

`SN^(2)`

B

`E1`

C

`E2`

D

`ElcB`

Text Solution

AI Generated Solution

The correct Answer is:
To determine which of the following reactions are stereospecific but not stereoselective, we will analyze the reactions: SN2, E1, E2, and E1CV. ### Step-by-Step Solution: 1. **Understanding Stereospecificity and Stereoselectivity**: - **Stereospecificity**: A reaction is stereospecific if the configuration of the starting material determines the configuration of the product. This means that a specific stereoisomer of the reactant will lead to a specific stereoisomer of the product. - **Stereoselectivity**: A reaction is stereoselective if it preferentially forms one stereoisomer over another from a mixture of stereoisomers. 2. **Analyzing SN2 Reaction**: - The SN2 reaction is stereospecific because it involves a backside attack on the substrate, leading to inversion of configuration. However, it is also stereoselective because it selectively forms one stereoisomer from a chiral substrate. - **Conclusion**: SN2 is not the answer. 3. **Analyzing E1 Reaction**: - The E1 reaction involves the formation of a carbocation intermediate. While the formation of the carbocation is specific, the elimination step can lead to a mixture of products (both E and Z isomers). - **Conclusion**: E1 is not stereospecific as it does not lead to a specific stereoisomer. 4. **Analyzing E2 Reaction**: - The E2 reaction is stereospecific because it requires anti-periplanar geometry for the elimination to occur. However, it can also lead to the formation of multiple stereoisomers depending on the substrate and the elimination pathway. - **Conclusion**: E2 is not the answer as it is also stereoselective. 5. **Analyzing E1CV Reaction**: - The E1CV (Elimination Unimolecular Conjugate Base) reaction is stereospecific because the initial step involves the loss of a beta-hydrogen to form a specific carbocation. However, the subsequent steps can lead to a mixture of products, including different stereoisomers (enantiomers or diastereomers). - **Conclusion**: E1CV is stereospecific but not stereoselective. ### Final Answer: The reaction that is stereospecific but not stereoselective is **E1CV**.

To determine which of the following reactions are stereospecific but not stereoselective, we will analyze the reactions: SN2, E1, E2, and E1CV. ### Step-by-Step Solution: 1. **Understanding Stereospecificity and Stereoselectivity**: - **Stereospecificity**: A reaction is stereospecific if the configuration of the starting material determines the configuration of the product. This means that a specific stereoisomer of the reactant will lead to a specific stereoisomer of the product. - **Stereoselectivity**: A reaction is stereoselective if it preferentially forms one stereoisomer over another from a mixture of stereoisomers. ...
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