A cell is destined to complete cell cycle

Options

A. When it enters post-mitolic phase
B. When it crosses restriction point
C. Only when it crosses `G_(0)` check point
D. When all check points are successfully crossed

Answer

To solve the question of when a cell is destined to complete the cell cycle, we need to analyze the different phases of the cell cycle and the associated checkpoints. Here is a step-by-step solution:

### Step 1: Understand the Cell Cycle Phases
The cell cycle consists of several phases:
- **Interphase** (which includes G1, S, and G2 phases)
- **Mitosis** (M phase)

### Step 2: Identify the Checkpoints
During the cell cycle, there are critical checkpoints that ensure the cell is ready to proceed to the next phase:
- **G1 Checkpoint**: Checks for DNA damage, growth factors, and nutrient availability.
- **G2 Checkpoint**: Ensures that DNA replication has been completed and checks for DNA damage.
- **M Checkpoint (Metaphase Checkpoint)**: Confirms that all chromosomes are properly attached to the spindle apparatus before proceeding to anaphase.

### Step 3: Analyze the Options
The question presents four options regarding when a cell is destined to complete the cell cycle:
1. When it enters the post-mitotic phase.
2. When it crosses the restriction point.
3. When it crosses the genome checkpoint.
4. When all the checkpoints are successfully crossed.

### Step 4: Determine the Correct Answer
To be destined to complete the cell cycle, a cell must successfully pass all the checkpoints. If any checkpoint fails, the cell may enter a resting state (G0) or undergo apoptosis (programmed cell death). Therefore, the correct answer is:

**Option 4: When all the checkpoints are successfully crossed.**

### Conclusion
A cell is destined to complete the cell cycle when it has successfully passed all the checkpoints, ensuring that it is fully prepared for division.

---