Initiation of condensation of chromatin material occurs in

Options

A. Prophase
B. Anaphase
C. Telophase
D. Metaphase

Answer

### Step-by-Step Text Solution

1. **Understanding Chromatin**: Chromatin is a complex of DNA and proteins found in the nucleus of eukaryotic cells. It exists in a loosely packed form during interphase, allowing for gene expression and DNA replication.

2. **Phases of Cell Division**: The cell cycle includes several phases: interphase, prophase, metaphase, anaphase, and telophase. Each phase has distinct characteristics and functions.

3. **Prophase**: During prophase, which is the first stage of mitosis, chromatin begins to condense into visible chromosomes. This is the initiation of the condensation process. The chromatin fibers become more tightly packed, forming distinct structures that can be identified as chromosomes.

4. **Metaphase**: In metaphase, the chromosomes are already highly condensed and aligned at the cell's equatorial plane. However, this stage does not initiate the condensation; it is merely a continuation of the process that began in prophase.

5. **Anaphase and Telophase**: In anaphase, the sister chromatids are pulled apart to opposite poles of the cell. During telophase, the chromosomes begin to de-condense back into chromatin as the cell prepares to divide.

6. **Conclusion**: The initiation of the condensation of chromatin material occurs during prophase.

### Final Answer
The initiation of condensation of chromatin material occurs in **prophase**.

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