The mitotic spindle disappears in

Options

A. Prophase
B. Metaphase
C. Anaphase
D. Telophase

Answer

To answer the question "The mitotic spindle disappears in:", we can analyze the stages of mitosis and identify when the mitotic spindle is no longer present.

### Step-by-Step Solution:

1. **Understanding Mitosis Stages**:
- Mitosis consists of several stages: prophase, metaphase, anaphase, and telophase. Each stage has distinct events that occur.

2. **Prophase**:
- During prophase, the mitotic spindle begins to form. Spindle fibers emerge from the spindle apparatus and attach to the kinetochores on the centromeres of the chromosomes. Therefore, the spindle is present, not disappearing.

3. **Metaphase**:
- In metaphase, the chromosomes align at the metaphase plate, and the spindle fibers are fully formed and attached to the kinetochores. The spindle is still present during this stage.

4. **Anaphase**:
- During anaphase, the centromeres split, and the spindle fibers contract, pulling the sister chromatids toward opposite poles of the cell. The spindle is actively functioning, so it does not disappear in this stage.

5. **Telophase**:
- In telophase, the sister chromatids have reached the opposite poles of the cell. This is the stage where the mitotic spindle begins to disappear as its function is complete. The nuclear membrane starts to reform around the two sets of chromosomes, indicating the end of mitosis.

6. **Conclusion**:
- Based on the analysis of each stage, the mitotic spindle disappears during **telophase**.

### Final Answer:
The mitotic spindle disappears in **telophase**.