Glycolysis

Options

A. Takes place in the mitochondria
B. Produces no ATP
C. Has no connection with electron transport chain
D. Reduces two molecules of `NAD^(+)` for every glucose molecule processed

Answer

### Step-by-Step Solution for Glycolysis

1. **Definition of Glycolysis**: Glycolysis is a metabolic pathway that converts glucose into pyruvate, producing a small amount of energy in the form of ATP. It is the first step in both aerobic and anaerobic respiration.

2. **Location of Glycolysis**: Glycolysis occurs in the cytoplasm of the cell. This is crucial to note because it distinguishes glycolysis from other processes in cellular respiration that take place in the mitochondria.

3. **Products of Glycolysis**: The end product of glycolysis is two molecules of pyruvate for every molecule of glucose that is processed. This is an important aspect of the glycolysis pathway.

4. **Energy Production**: During glycolysis, a net gain of 2 ATP molecules is produced. This is significant because ATP is the primary energy currency of the cell.

5. **NAD+ Reduction**: Glycolysis also involves the reduction of NAD+ to NADH. For every glucose molecule processed, two molecules of NAD+ are reduced to NADH. This is essential for the continuation of cellular respiration as NADH will be used in the electron transport chain.

6. **Connection to Electron Transport Chain**: Although glycolysis itself does not involve the electron transport chain, the products (NADH and pyruvate) are crucial for the subsequent stages of cellular respiration, including the electron transport chain.

### Conclusion
Based on the above points, the correct statement regarding glycolysis is that it reduces two molecules of NAD+ for every glucose molecule processed.