Cybrid is a result of

Options

A. Fusion of cytoplasm and nuclei of the two somatic cells
B. Fusion of cytoplasm of two somatic cell but the nuclei remain unfused
C. Fusion of cytoplasm of two somatic cells occurs but the nucleus of one cell persists, and the nucleaus of other degenerates
D. Fusion of cytoplasm of two somatic cells take place but one part of the nucieus of one cell fuses with the entire nucleus of second cell

Answer

### Step-by-Step Solution:

1. **Understanding Cybrid**:
- A cybrid, also known as a cytoplasmic hybrid, is a type of hybrid cell that contains cytoplasm from one cell and nucleus from another. It is primarily a eukaryotic cell line.

2. **Characteristics of Cybrids**:
- Cybrids are formed by the fusion of the cytoplasm of two somatic cells.
- Importantly, the cytoplasts used in creating cybrids are enucleated, meaning they do not have a nucleus.

3. **Gene Contribution**:
- In the formation of a cybrid, the nuclear genes from one cell are combined with the mitochondrial genes (cytoplasmic genes) from both cells involved in the fusion.

4. **Evaluating the Options**:
- **Option 1**: Fusion of cytoplasm and nuclei of two somatic cells - Incorrect, as the nuclei do not fuse in cybrids.
- **Option 2**: Fusion of cytoplasm of two somatic cells but the nuclei remain unfused - Incorrect, as this does not accurately describe the cybrid formation.
- **Option 3**: Fusion of cytoplasm of two somatic cells occurs but the nucleus of one cell persists and the nucleus of another cell degenerates - Correct, as this accurately describes the formation of a cybrid.
- **Option 4**: Fusion of cytoplasm of two somatic cells takes place but one part of the nucleus of one cell fuses while the entire nucleus of the second cell - Incorrect, as this does not happen in cybrid formation.

5. **Conclusion**:
- The correct answer is the third option, which states that the fusion of cytoplasm of two somatic cells occurs, but the nucleus of one cell persists while the nucleus of the other cell degenerates.