A: The nucleus of plasma cell has cart wheel appearance.
R: Nucleus contains peripheral clumps of heterochromatin.

Options

A. Tendon-specialized connective tissue
B. Adipose tissue-dence connective tissue
C. Areolar tissue-loose connective tissue
D. Cartilage loose connective tissue

Answer

### Step-by-Step Solution:

1. **Understanding the Assertion**:
- The assertion states that the nucleus of plasma cells has a "cartwheel appearance." Plasma cells are derived from B lymphocytes and are crucial for antibody production in the immune response.

2. **Analyzing the Reason**:
- The reason provided is that the nucleus contains "peripheral clumps of heterochromatin." Heterochromatin is a form of DNA that is tightly packed and is typically found at the periphery of the nucleus.

3. **Connecting the Assertion and Reason**:
- The cartwheel appearance of the nucleus can be attributed to the arrangement of heterochromatin. The clumping of heterochromatin at the periphery of the nucleus creates a visual effect that resembles a cartwheel.

4. **Validity of Both Statements**:
- Both the assertion and the reason are true. The nucleus of plasma cells does indeed have a cartwheel appearance due to the presence of peripheral clumps of heterochromatin.

5. **Conclusion**:
- Since both the assertion and the reason are true, and the reason correctly explains the assertion, we conclude that the option is correct.

### Final Answer:
Both the assertion and the reason are true, and the reason correctly explains the assertion.

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