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Co-factor whose association with the apo...

Co-factor whose association with the apoenzyme is only transient

A

Prosthetic group

B

Coenzyme

C

Metal ions

D

All of these

Text Solution

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The correct Answer is:
### Step-by-Step Solution 1. **Understanding the Terms**: - **Apoenzyme**: This is the protein part of an enzyme, which requires a cofactor to become active. - **Holoenzyme**: This is the complete enzyme, which includes the apoenzyme and its associated cofactors. 2. **Identifying Cofactors**: - Cofactors are non-protein molecules that assist in enzyme activity. They can be classified into three categories: - **Coenzymes**: Organic molecules that are tightly bound to the enzyme. - **Prosthetic Groups**: Similar to coenzymes but are usually bound more tightly and permanently. - **Essential Ions (Metal Ions)**: These are often metal ions that can associate with the enzyme. 3. **Association Types**: - The association of cofactors with apoenzymes can be classified as: - **Tightly Bound**: Coenzymes and prosthetic groups are usually tightly bound to the enzyme. - **Loosely Bound**: Essential ions (metal ions) are loosely associated with the enzyme, meaning their binding is transient. 4. **Analyzing the Question**: - The question specifically asks for the cofactor whose association with the apoenzyme is only transient. This indicates that we are looking for a cofactor that does not bind permanently. 5. **Conclusion**: - Since essential ions (metal ions) are loosely bound and their association with the apoenzyme is transient, the correct answer to the question is **metal ions**. ### Final Answer The co-factor whose association with the apoenzyme is only transient is **metal ions**. ---
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