select the odd one w.r.t disease with prion as causative organisms

Options

A. Scrapie disease in sheep
B. Cholera
C. Creutzfeldt jakob disease
D. Bovine spongiform encephaloathy

Answer

To solve the question of selecting the odd one out with respect to diseases caused by prions, we will analyze each option provided:

1. **Scrapie Disease in Sheep**:
- Scrapie is a neurodegenerative disease caused by prions. It affects sheep and is characterized by the degeneration of the nervous system. Therefore, this option is not the odd one out.

2. **Creutzfeldt-Jakob Disease**:
- Creutzfeldt-Jakob disease (CJD) is a rare but fatal neurodegenerative disorder in humans caused by prions. This disease is also not the odd one out.

3. **Bovine Spongiform Encephalopathy (BSE)**:
- Bovine Spongiform Encephalopathy, commonly known as "mad cow disease," is caused by prions and affects cattle. Like the previous options, this is also not the odd one out.

4. **Cholera**:
- Cholera is an infectious disease caused by the bacterium Vibrio cholerae. It is not caused by prions, making it the odd one out in this list.

**Conclusion**: The odd one out with respect to diseases caused by prions is **Cholera**.

### Step-by-Step Solution:
1. **Identify the diseases listed in the options**.
2. **Determine the causative agents of each disease**:
- Scrapie: Caused by prions.
- Creutzfeldt-Jakob Disease: Caused by prions.
- Bovine Spongiform Encephalopathy: Caused by prions.
- Cholera: Caused by the bacterium Vibrio cholerae.
3. **Compare the causative agents**:
- Identify which diseases are caused by prions and which is caused by bacteria.
4. **Select the odd one**:
- Since Cholera is caused by bacteria and not by prions, it is the odd one out.