Which of the following is considered as graveyard of RBCs?

Options

A. Thymus
B. Spleen
C. Pancreas
D. Bone marrow

Answer

To answer the question "Which of the following is considered as the graveyard of RBCs?" we will analyze each of the provided options step by step.

### Step 1: Understand the Question
The question asks for the organ or structure that is known for the destruction or breakdown of red blood cells (RBCs) after their lifespan.

### Step 2: Analyze the Options
1. **Thymus**:
- The thymus is primarily involved in the maturation of T-lymphocytes (a type of white blood cell). It does not play a role in the destruction of RBCs.
- **Conclusion**: This option is incorrect.

2. **Spleen**:
- The spleen is known as the graveyard of RBCs because it is responsible for filtering and removing old or damaged red blood cells from circulation.
- It contains macrophages that ingest and break down these cells.
- Approximately 2.5 million RBCs are destroyed in the spleen every second.
- **Conclusion**: This option is correct.

3. **Pancreas**:
- The pancreas is involved in digestion and the production of digestive enzymes. It does not have a role in the destruction of RBCs.
- **Conclusion**: This option is incorrect.

4. **Bone Marrow**:
- Bone marrow is the site of RBC production, not destruction. It is where new red blood cells are formed before entering the bloodstream.
- **Conclusion**: This option is incorrect.

### Step 3: Final Answer
Based on the analysis of the options, the correct answer is **Spleen**, as it is considered the graveyard of RBCs.

---