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Give the following conversion acetaldehy...

Give the following conversion acetaldehyde `rarr` alanine.

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To convert acetaldehyde (CH3CHO) to alanine (C3H7NO2), we can follow these steps: ### Step 1: Nucleophilic Addition of Hydrogen Cyanide - **Reaction**: Acetaldehyde reacts with hydrogen cyanide (HCN). - **Mechanism**: The cyanide ion (CN-) acts as a nucleophile and attacks the carbonyl carbon of acetaldehyde. The oxygen atom of the carbonyl group gains a negative charge, leading to the formation of a cyanohydrin. **Equation**: \[ CH_3CHO + HCN \rightarrow CH_3C(OH)(CN) \] ### Step 2: Formation of an Amine - **Reaction**: The cyanohydrin formed in Step 1 is treated with ammonia (NH3). - **Mechanism**: The amine group (NH2-) from ammonia attacks the carbon atom that is bonded to the hydroxyl group (OH) and the cyanide group (CN). A water molecule is eliminated in this process. **Equation**: \[ CH_3C(OH)(CN) + NH_3 \rightarrow CH_3C(NH_2)(CN) + H_2O \] ### Step 3: Acidic Hydrolysis - **Reaction**: The product from Step 2 undergoes acidic hydrolysis. - **Mechanism**: The cyanide group (CN) is converted to a carboxylic acid (COOH) through hydrolysis. The reaction involves the addition of water and the presence of an acid catalyst. **Equation**: \[ CH_3C(NH_2)(CN) + H_2O \rightarrow CH_3C(NH_2)(COOH) \] ### Final Product - The final product is alanine (C3H7NO2), which has the structure: \[ CH_3CH(NH_2)COOH \] ### Summary of the Reaction Steps 1. **Nucleophilic addition of HCN to acetaldehyde** to form a cyanohydrin. 2. **Reaction with ammonia** to form an intermediate amine. 3. **Acidic hydrolysis** of the intermediate to convert the cyanide to a carboxylic acid, yielding alanine.

To convert acetaldehyde (CH3CHO) to alanine (C3H7NO2), we can follow these steps: ### Step 1: Nucleophilic Addition of Hydrogen Cyanide - **Reaction**: Acetaldehyde reacts with hydrogen cyanide (HCN). - **Mechanism**: The cyanide ion (CN-) acts as a nucleophile and attacks the carbonyl carbon of acetaldehyde. The oxygen atom of the carbonyl group gains a negative charge, leading to the formation of a cyanohydrin. **Equation**: \[ ...
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RESONANCE ENGLISH-BIOMOLECULES-Ex-2(Subjective)Part-I
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  2. Write the anomer, the epimer, enantiomer of the following aldose, Als...

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  3. Draw two anomers of D-fructose.

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  4. The specific rotation of two glucose anomers are alpha = + 110^(@) and...

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  5. Consider an amylose chain of 4000 glucose unit. At how many cleavage r...

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  6. The density of methane at 3.0 atm pressure and 27^0C is :

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  7. The density of methane at 5.0 atm pressure and 27^0C is :

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  8. Find rms speed of oxygen molecules at temperature 27^(@)C.

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  9. On which side of neutrality (pH-7), the isoelectric point of the follo...

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  10. Glutomic acid (A) has isoelectric point 3.22 (a) What is the most li...

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  11. The density of Carbon dioxide at 3.0 atm pressure and 27^0C is :

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  12. The density of Carbon dioxide at 5.0 atm pressure and 27^0C is :

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  13. The density of Carbon dioxide at 4.0 atm pressure and 27^0C is :

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  14. Distinguish between (a) Glycine and acetamide (b) alpha -, beta - ...

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  15. An octapeptide (Mol.wt = 516 g) on complete hydrolysis given glycine a...

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  16. Give the amino acid sequence of the following polypeptides using the d...

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  17. Glutamic acid has lower isoelectric point while glutamine H(2)N-overse...

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  18. Give the following conversion acetaldehyde rarr alanine.

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  19. Complete the following reactions

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  20. The density of Carbon dioxide at 6.0 atm pressure and 27^0C is :

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